Green Synthesis of Anti-Aging Gel Mask Contains Essential Oils Based Nanoemulsions

Abstract

This study investigates the formulation and evaluation of eco-friendly nanoemulsion-based gels (GN1–GN6) that incorporate natural ingredients, specifically lavender oil and myrtle oil. These oils are recognized for their anti-inflammatory, antioxidant, antiseptic, and immune-boosting properties, making them ideal candidates for counteracting the effects of aging. The primary objective was to develop a stable and therapeutically effective topical gel contain environmentally friendly natural oils in nanoemulsion form to be promising product against photoaging and chronological aging. Utilizing a microwave-based method, a pseudoternary phase plot was created, leading to the assessment of six distinct nanoemulsion formulations (NE1–NE6) through thermodynamic and characterization processes that were used to prepare nanoemulsion-based gels (GN1–GN6). The results revealed that all nanoemulsion formulations exhibited favorable surface charge, low polydispersity indices, robust thermodynamic stability, and nanosized particle dimensions. Additionally, the evaluation of the gel formulations (GN1–GN6) demonstrated stable organoleptic properties, suitable pH and spreadability values, acceptable viscosity, no skin irritation and good biological membrane permeation ability. The therapeutic efficacy of the various chemical constituents within the essential oil-based nanoemulsions, combined with the positive evaluation results of the nanoparticle-based gels, positions these formulations as promising natural masks. They effectively restore skin health and protect against the adverse effects of aging and environmental stressors, particularly sun exposure.