Preparation of a Medicinal Formula as Emulsion Spray from Oil Extracts of Thyme, Spearmint and Clove to Treat Oral Ulcers in Animals and FMD in Cattle

Abstract

Oral ulcers are common occurrences in animals for many reasons, including accidental injuries that occur during the consumption of feed or food, and may be bacterial and fungal or viral causes such as foot-and-mouth disease, which is usually accompanied by ulcers in the mouth, udder and foot (FMD), which leads to the animal's abstinence from food and then death so to find ways that solve this problem a pharmaceutical formula had been prepared from extract oils mint, thyme and cloves called it (mint vet). The oils were extracted by water evaporation then examined by GC-MS and attended many formulations until reaching the until reaching the perfect consistency and stability where the pharmaceutical form was white emulsion kept inside a spray bottle given in the form of a mouthwash. The biological test stability was conducted on the product for six months at two temperatures one of them cold degree 4°C and the other is room temperature 25°C to determine the expiration   date and the best storage conditions, it has been compare with stander Gentamicin and Nystatin the inhibition zone of formula was higher than stander inhibition zone, high temperature was avoided because the product contains essential oil, the expiry date was calculated two years and store at less 15°C. The formula has been tasted in veterinary hospitals in Al-Rashedia and Baghdad, the report had proved the efficiency of the mouth wash and there are significant responses, when it’s used to treat Foot and Mouth Disease FMD without any side effect.